Signal Transduction Reagents and Kits
Enzo Life Sciences BAY 61-3606. hydrochloride (1mg). CAS: 648903-57-5
Cell permeable, potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50=10nM). Highly selective if compared to other kinases; shows no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src up to concentrations of 4.7µM. Anti-inflammatory and orally active. Exhibits good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models. Alternative name: 2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide . HCl. Purity: ≥98% (HPLC(UV)). Appearance: Yellow solid. Solubility: Soluble in water (30mg/ml), DMSO (2mg/ml) or methanol (1mg/ml). Long Term Storage: -20°C.
Medchemexpress LLC Syk-IN-1 | 1491150-77-6 | 99.18% | 100 MG
Syk-IN-1 is a potent Syk inhibitor, with an IC50 of 35 nM. It is intended for research use only.
- Potent Syk inhibitor with an IC50 of 35 nM.
- Offered as a solid for various research applications.
- Optimal storage for powder: -20°C for 3 years or 4°C for 2 years.
- Optimal storage for solvent: -80°C for 6 months or -20°C for 1 month.
Enzo Life Sciences 8-Bromo-cGMP (50mg). CAS: 51116-01-9
A cell-permeable cGMP analog which is more resistant to phosphodiesterases than cGMP and which preferentially activates cGMP-dependent protein kinase. It inhibits thrombin stimulated arachidonic acid release in human platelets. Purity: ≥96% (HPLC). Solubility: Soluble in water (25mg/ml) or aqueous buffers. Sparingly soluble in methanol (4mM). Insoluble in DMSO, dimethyl formamide and 96% ethanol. Long Term Storage: -20°C.
Echelon Biosciences Research Labs PI(3,4)P2 PolyPIPosomes 0.1 mL
PolyPIPosomes are polymerized liposomes that show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents. PolyPIPosomes are provided as a 1mM total lipid solution containing 5% PIP. Each order of 250 L or 1 mL of PolyPIPosomes includes 100 L of Control PolyPIPosomes. This item is non returnable
Echelon Biosciences Research Labs 1-Hydroxy-2-methyl-2-buten-4-yl 4-diphosphate (HDMAPP) 10 mg
1-Hydroxy-2-methyl-2-buten-4-yl 4-diphosphate (HDMAPP or HMBPP) is an intermediate in the non-mevalonate pathway and is biosynthesized from 2-C-Methyl-D-erythritol 2,4-cyclophosphate (cMEPP) by IspG (GcpE). It is the substrate for IspH (LytB) yielding IPP and DMAPP. In addition, HDMAPP is the most potent VgVd T-cell activator identified. This item is non returnable
Apexbio Technology LLC Calpain and cathepsin B inhibitor, selective 88191-84-8. MFCD28137700
Calpain and cathepsin B inhibitor, selective 88191-84-8. MFCD28137700
Meso Scale Discovery Phos Tyr694TTL STAT5ab WCL 5
The Meso Scale Discovery Phospho-Tyr694/Total STAT5A/B Whole Cell Lysate Kit (K15163D) is a kit for detecting phosphorylated STAT5A/B and total STAT5A/B in cell lysates The kit contains a 96-well plate coated with capture antibodies against STAT5A/B and phospho-STAT5A/B Tyr694 It also includes detection antibodies and buffers needed to perform the assay The electrochemiluminescent detection allows for high sensitivity and a broad dynamic range This kit can be used to monitor STAT5A/B phosphorylation and activation in response to cytokines growth factors and drugs that modulate the JAK/STAT pathway It requires a low amount of sample and provides high-quality data
Enzo Life Sciences Calpeptin (10mg). CAS: 117591-20-5
Membrane permeable inhibitor of calpain I and II, cathepsin L and cathepsin K (IC50=0.11 nM). Promotes neurite elongation in differentiating PC12 cells. Prevents Ca2+-ionophore induced degradation of actin binding protein and P235 in platelets. Inhibits myosin light chain phosphorylation in platelets stimulated by collagen, ionomycin (ALX-450-006) or thrombin. Inhibits LPS induced iNOS transcription and NF-κB activation, possibly via proteasome inhibition. Alternative name: Z-Leu-norleucinal, N-Benzyloxycarbonyl-L-leucyl-norleucinal. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml), 100% ethanol (25mg/ml or dimethyl formamide (5mg/ml). Long Term Storage: -20°C.
Abcam Glucose 6 Phosphate Dehydrogenase Activity Assay Kit (Fluorometric)
Glucose 6 Phosphate Dehydrogenase Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Quanterix Inc TSA(TM) FLUORESCEIN SYSTEM (50
TSA, Fluorescein System, for 50-150 Slides. These systems are designed for direct fluorescence detection in ISH or IHC procedures.
Qiagen, Inc. CIGNAL E2F REPORTER ASSAY KIT
NC3851988 CIGNAL E2F REPORTER ASSAY KIT
Quanterix Inc TSA CYANINE 3 SYSTEM (50-150 S
TSA Cyanine 3 System, for 50-150 Slides. These systems are designed for direct fluorescence detection in ISH or IHC procedures.
Echelon Biosciences Research Labs GERANYLGERANIOL 10 mg
(E,E,E)-Geranylgeraniol is an intermediate in the biosynthetic pathway of vitamins E & K and is linked to proteins via post-translational modification. This item is non returnable
Creative Biomart Human F7/Coagulation factor VII human
The product is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Enzo Life Sciences L-cis-Diltiazem HCl (5mg). CAS: 42399-54-2
Blocks cyclic nucleotide-gated calcium channels. Purity: ≥98%. Solubility: Soluble in water (>10mg/ml). Long Term Storage: Ambient.